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Mitigation of biochemical and histological effects of bromobenzene on the hepatic system in rats by the Indian herbal drug formulation Triphala
B.U. Lavinya, M. Vedi, S.J. Martin, N. Srilekha, B.S. Kumar, , E.P. Sabinia
Published in Scientific Publishers
2015
Volume: 92
   
Issue: 4
Pages: 566 - 569
Abstract
The present study is ail attempt to evaluate the hepatoprotective and anti-oxidant properties of Triphala against bromobenzene (BB) induced hepatotoxicity in rats. Hepatotoxicity was induced in rats by a single oral dose of BB (10 mmol/kg b.w) on first day of the study. Two different doses (250 mg/kg b.w and 500 mg/kg b.w) of Triphala were administered to the bromobenzene intoxicated rats for 8 days. The standard hepatoprotective drug siiyinarin was used as reference drug for comparison. Bromobenzene treatment resulted in a significant (p < 0.05) decrease in the activities of anti-oxidant enzymes; cataiase (CAT), superoxide dismutase
About the journal
JournalJournal of the Indian Chemical Society
PublisherScientific Publishers
ISSN00194522