One-pot synthesis of quinolinyl amine nitriles, 8, was accounted from quinoline-3-carbaldehyde, 7, and amines (benzylic, aromatic, aliphatic, or hetero-aromatic) using Zn(CN)2/trifluoroethanol (TFE) system, an eco-friendly, and ambient protocol. Antidiabetic, anti-inflammatory, antioxidant, and molecular docking studies of 8a–l revealed moderate-to-good activity. © 2020, © 2020 Taylor & Francis Group, LLC.

Nawaz Khan F

Department of Chemistry

School of Advanced Sciences

Vellore Campus

R. Dalavai

K. Gomathi

K. Naresh

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

One-Pot Synthesis of Quinolinyl Amino Nitriles and Their Antidiabetic, Anti-inflammatory, Antioxidant, and Molecular Docking Studies

Polycyclic Aromatic Compounds

Journal	Data powered by TypesetPolycyclic Aromatic Compounds
Publisher	Data powered by TypesetTaylor and Francis Inc.
ISSN	10406638