Photon propagation through tissue phantoms, made of heart, adipose, and spleen tissues was simulated by Monte Carlo procedure. To detect the presence of deep-seated abnormalities, phantoms of heart with adipose and spleen tissues embedded into it were created and simulations were performed to scan the tissue surface with a source and four detector model. Profiles drawn showed variation in parameters such as backscattered intensity in regions where adipose and spleen tissues were embedded. This study shows that depending on the type of embedded tissue the backscattered fraction as measured at 2 mm from the input fiber is altered. This is enhanced for adipose and decreased for spleen tissue. This is not only shown in scanned profiles on the surface but also in constructed images.

Jeeva J-B

Department of Sensor and Biomedical Technology

School of Electronics Engineering

Vellore Campus

Singh M.

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

Optical parameters of embedded abnormalities in tissues as determined by Monte Carlo simulation.

Electromagnetic Biology and Medicine

Thenormalized backscattered intensity (NBI) profiles at various locations of human thorax by multiprobe laser reflectometer are obtained. These data after digitization, interpolation, and filtering are color-coded and displayed as images on the outline of the human thorax. For optical characterization of tissues in terms of their parameters, scattering and absorption coefficients and the anisotropy parameter (g) are obtained by matching the measured NBI profile with that as obtained by Monte Carlo simulation procedure. Corresponding to the variation of the NBI over the various regions, the optical parameters show their respective changes. The maximum absorption and minimum scattering coef- ficients are observed at the areola, clavicle, sternum, scapula, and vertebral column. The minimum absorption and maximum scattering coefficients are observed at the pectoralis major of chest and rectus abdominis of abdomen regions, as compared to the other regions, attributed to their tissue compositional variations. To visualize the various tissues in lower regions of the thorax, the color-coded scheme of the NBI variation, as measured by the third fiber, is further expanded. By this procedure, the outlines of the heart and lungs, as detected through intercostals regions, are observed, which is in good agreement with that as determined by the chest radiograph of the same subject taken in PA position. Similarly the lower sections of the liver and stomach, due to their distinct optical parameters, are also observed. © 2006 IEEE.

IEEE Transactions on Biomedical Engineering

Laser reflectance imaging of human chest for localization of internal organs

Medical & Biological Engineering & Computing

Can we see epithelium tissue structure below the surface using an optical probe?

Journal of Modern Optics

A feature parameter of optical diffuse reflectance on normal and malignant human breast tissue

The normalized back-scattered intensity (NBI) profiles at various locations on the human thorax of a subject were obtained by multi-probe laser reflectometer. The laser radiations are guided by an optical fiber onto the human thorax tissues and the backscattered radiations are collected by three optical fibers placed at distance of 2mm, 4mm and 6mm from the input fiber. The data collection of the human thorax tissue is carried out using an automatic non-contact scanning system controlled by the personal computer. The data after digitization, interpolation and filtering, are color-coded and displayed on the outline of the human thorax. These NBI pattern vary depending on the muscular, anatomical and vascular compositions and also on percentage of fat composition at various locations. For optical characterization the optical parameters, scattering (μs) and absorption (μa) coefficients and the anisotropy parameter (g) at each location on the human thorax, by matching of reflectance profiles with that as simulated by a Monte Carlo simulation (MCS) procedure were determined. The point-to-point variations of the optical parameters and NBI variations at various regions of the human thorax tissues are studied. © 2007 IEEE.

Proceedings of ICSCN 2007: International Conference on Signal Processing Communications and Networking

Non-invasive imaging and characterization of human thorax tissues by non-contact scanning multi-probe laser reflectometry and Monte Carlo simulation

NeuroImage

Three dimensional optical imaging of blood volume and oxygenation in the neonatal brain

Optical parameters of embedded abnormalities in tissues as determined by Monte Carlo simulation

Journal	Electromagnetic Biology and Medicine
Publisher	Informa UK Limited
ISSN	1536-8378
Open Access	0