Gunasekar Ramachandran

Kulathu I. Sathiyanarayanan.

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

&nbsp;

&nbsp;

VIT University

Recent Patents on Catalysis

A highly efficient protocol has been developed for the synthesis of aminals from γ-butyrolactam and benzaldehyde using iodine as Lewis acid catalyst. The attack of γ-butyrolactam nucleophile to intermediate N-acyliminium ion was more favorable, when aryl aldehyde bears the electron donating group (EDG). Iodine plays a key role in these reaction transformations. This current mild protocol is environmentally benign and cost-effective method for the synthesis of industrially and pharmaceutically useful scaffolds. © 2013 Elsevier Ltd. All rights reserved.

Tetrahedron Letters

Efficient iodine catalyzed chemoselective synthesis of aminals—an access to N,N-acetals by the addition of lactams to N-acyl imines

A green trend and efficient method for the synthesis of N-substituted γ, δ and ε-lactam derivatives has been developed through one pot multi-component reaction under environmentally benign reaction conditions using FeCl3 as a green catalyst with high atom economy. The present green synthetic protocol shows fascinating properties such as enhanced yield in solvent-free conditions, with high reaction rate, easy workup and absence of column chromatography and also avoids the use of ligands or additives. The versatility of the reaction has been ascertained by using various substituted benzaldehydes, anilines and homologues of lactams. © 2013 The Royal Society of Chemistry.

Journal	Recent Patents on Catalysis
Publisher	Bentham Science Publishers Ltd.
ISSN	2211-548X
Open Access	0