Vijayakumar V

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Reddy B.P

Rajesh K

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

PEG400-Lithium Carbonate Catalyzed Synthesis of 1,4-Dihydropyridines under Solvent-free Conditions

Organic Preparations and Procedures International

Abstract Synthesis of 1,4-dihydropyridines by three-component condensation reaction of aldehyde, 1,3-dicarbonyl compounds, and ammonium acetate have been found to be efficiently catalyzed by uranyl nitrate hexahydrate [UO2(NO3)2 ·6H2O] at room temperature under ultrasound irradiation. This novel synthetic method offers the advantages of high yields, short reaction times, simplicity, and easy workup compared to the conventional methods reported in the literature. © 2014 Springer Science+Business Media Dordrecht.

Research on Chemical Intermediates

Ultrasound-mediated, uranyl nitrate hexahydrate-catalyzed synthesis of 1,4-dihydropyridines under mild conditions

The reaction of various substituted 24-dichloroquinolines with methyl 4-(4-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate has been carried out in the presence of powdered K2CO3 as a mild and efficient base at controlled temperature leading to novel 2-chloroquinoline-based polyhydroquinoline with high regioselectivity. All the synthesized compounds were characterized through IR, NMR, and mass spectral data. © 2013 Springer Science+Business Media Dordrecht.

Regioselective synthesis of novel 2-chloroquinoline-based methyl 4-(4-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylates

Highly regioselective reaction of some substituted 2,4-dichloroquinolines with symmetrical 1,4-dihydropyridines, leading to novel quinoline derivatives of DHPs, has been achieved in the presence of powdered K2CO 3, as a mild and efficient base, at moderate temperature. All the synthesized compounds were characterized by use of IR, NMR, and mass spectral data. © 2013 Springer Science+Business Media Dordrecht.

Regioselective synthesis of novel 2-chloroquinoline derivatives of 1,4-dihydropyridines

The 1,4-dihydro-pyridine ring in the title hydrate, C17H 18BrNO2·H2O, has a flattened-boat conformation, and the benzene ring is occupies a position orthogonal to this [dihedral angle: 82.19 (16)°]. In the crystal packing, supra-molecular arrays mediated by N - H⋯Owater and Owater - H⋯Ocarbonyl hydrogen bonding are formed in the bc plane. A highly disordered solvent mol-ecule is present within a mol-ecular cavity defined by the organic and water mol-ecules. Its contribution to the electron density was removed from the observed data in the final cycles of refinement and the formula, mol-ecular weight and density are given without taking into account the contribution of the solvent mol-ecule.

Fulltext

Acta Crystallographica Section E Structure Reports Online

1-[5-Acetyl-4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridin-3-yl]ethanone monohydrate

ChemInform

ChemInform Abstract: Synthesis of 3-((2,3-Dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl) alkyl) 1,4-Dihydropyridine-3,5-dicarboxylate Derivatives as Calcium Channel Modulators.

ChemInform Abstract: Synthesis of Some 1,4-Dihydropyridine Derivatives and Their Calcium Antagonistic Activity.

ChemInform Abstract: Synthesis of 1,4-Dihydropyridines and Their Hypotensive Activity.

Tetrahedron Letters

Synthesis of 3,4-dihydropyrimidin-2(1H)-ones and 1,4-dihydropyridines using ammonium carbonate in water

Journal	Organic Preparations and Procedures International
Publisher	Informa UK Limited
ISSN	0030-4948
Open Access	0