In secured communication, pseudo-random number generators (PRNGs) are widely used to generate random sequences. This paper presents a novel D flip flop and standard EX-NOR gate to realize a Quantum dot Cellular Automata (QCA) based PRNG. For the purpose of comparison, QCA based PRNG is implemented with existing D flip flops. The proposed D flip flop comprises a cell count of 24 with area of 0.02 µm2 and delay of 0.05 ps, total power dissipation for D flip flop is 40.30 meV, 49.76 meV and 61.90 meV for different tunneling energy level of 0.5 Ek, 1.0 Ek and 1.5 Ek, respectively at temperature of 2 Kelvin. The implemented PRNG configurations are simulated using QCA Designer tool for area and delay. Power dissipation of D flip flop is analyzed using QCA Pro simulator tool. From the simulated results, it may be noted that PRNG with novel D flip flop realization achieves low power, low area and less delay compared to other PRNG realization. © 2020