In the present work, silk fiber (SF) and methylcellulose (MC) composites were fabricated by solvent casting method and characterized in detail. The interactions between SF/MC composites were studied in detail by Fourier transform infrared (FT-IR) spectroscopy and powder X-ray diffraction (XRD). The surface morphology and thermal stability were studied. Viscosity, thickness, folding endurance, tensile strength and antioxidant activity were analyzed for different ratios of SF/MC composite. Antimicrobial activity, in vitro biomimetic mineralization, hemocompatibility and cell viability of the SF/MC composite were studied. The deposition of calcium and phosphorus ions from simulated body fluid (SBF) onto SF/MC composite surface was evidenced from XRD, FT-IR and SEM–EDS. Inductively coupled plasma-optical emission spectrometry analysis (ICP-OES) was utilized to analyze leaching of Ca and P ions from the SBF. Hemolytic assay proves that the composites were compatible with blood and hemolytic ratio is found to be less than 5%. The MTT assay test against MG-63 suggests that the SF/MC composites are promising biomaterials for bone tissue engineering applications. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.

Sumathi S

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Narayanan V

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

Polymer Bulletin

Zn-Mn HAP (Zinc and Manganese substituted Hydroxyapatite), CMC (Carboxymethyl cellulose)/PVP (Polyvinyl pyrrolidone) and (Zn-Mn HAP)/CMC/PVP (Zn = Mn = 0.05, 0.1 M) were prepared by hydrothermal and electrospinning methods respectively. The prepared composites were characterized using powder X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) with Energy Dispersive X-Ray Analysis (EDAX) to examine the phase formation, functional groups and surface morphology. FTIR spectra of the composite confirmed the funcitonal groups present in the composite. SEM images showed the fiber formation and the incorporation of Zn-Mn HAP into the fiber structures. The physical properties like porosity, swelling and tensile strength was studied for the prepared composites. 0.1 M of (Zn-Mn HAP)/CMC/PVP (20, 40, 60 wt% of Zn-Mn HAP composite) showed good physical properties, in which the 60 wt% showed 98% of porosity with least swelling and the tensile strength was measured to be 67 MPa. Highest zone of inhibition was observed against the microbial organisms using this 60 wt% of 0.1 M of (Zn-Mn HAP)/CMC/PVP composite and it was also found to be hemocompatible with hemolysis value less than 3% when compared to other composites. The biocompatibility of the composite was evaluated using human osteoblast cells (HOS). © 2019 Elsevier B.V.

International Journal of Biological Macromolecules

Zinc and manganese substituted hydroxyapatite/CMC/PVP electrospun composite for bone repair applications

Copper substituted hydroxyapatite (Ca10-xCux(PO4)(6)(OH)(2) (x=0.05-2.0), and fluorapatite Ca10-xCux(PO4)(6)(F)(2) (x=0.05-2.0) were synthesized by co-precipitation method. The synthesized compounds were characterized by powder X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy and thermo gravimetric analysis. The antimicrobial activity of the synthesized compounds were tested against the organisms Escherichia coli (Gram negative bacteria), Staphylococcus aureus (Gram positive bacteria) and Candida albicans (yeast) quantitatively by spread plate method. 100% reduction in the number of colonies were observed with Ca10-xCux(PO4)(6)(F)(2) (x=0.15-0.5) against E. colt. This material can be considered as good antibacterial agent for bone implantation.

Ceramics International

Copper substituted hydroxyapatite and fluorapatite: Synthesis, characterization and antimicrobial properties

Applied Surface Science

Cellulose acetate membranes functionalized with resveratrol by covalent immobilization for improved osseointegration

Vacuum

Synthesis and characterization of cellulose acetate-hydroxyapatite micro and nano composites membranes for water purification and biomedical applications

Silk fibroin/chitosan scaffold with tunable properties and low inflammatory response assists the differentiation of bone marrow mesenchymal stem cells

Artificial Cells, Nanomedicine, and Biotechnology

Fabrication and characterization of graphene-based hybrid nanocomposite: assessment of antibacterial potential and biomedical application

Preparation, characterization and in vitro biological study of silk fiber/methylcellulose composite for bone tissue engineering applications

Journal	Data powered by TypesetPolymer Bulletin
Publisher	Data powered by TypesetSpringer Science and Business Media LLC
ISSN	0170-0839
Open Access	0