A new anion selective chemosensor L was derived through a direct condensation reaction between pyridoxal and thiosemicarbazide.

Kumar R

Computer Science

School of Computer Science and Engineering

Chennai Campus

Ashok Kumar S-K

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Sharma D

Moirangthem A

Kuwar A

Callan J.F

Basu A

Sahoo S.K.

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

RSC Advances

This manuscript introduced a new optically active chemosensor L containing rhodamine 6G as the fluorogenic unit and the vitamin B6 cofactor pyridoxal 5′-phosphate (PLP) as the metal ions binding unit. Sensor L showed a significant turn-on fluorescence at 550 nm selectively in the presence of Al3+ and Cr3+ ions due to the complexation prompted opening of the spirocyclic ring. Using sensor L, the concentration of Al3+ and Cr3+ ions can be detected down to 0.41 µM and 2.33 µM, respectively. Sensor L formed a metal complex in 1:1 binding stoichiometry in solution with the estimated binding constant of 11,310 M−1 and 8373 M−1 with Al3+ and Cr3+, respectively. The probable 3D structure and the electronic properties of L and its complexes were proposed by semi-empirical PM6 method. Further, the bioimaging experiments were performed to examine the potential of L to detect the intracellular Al3+ and Cr3+ ions present in the live HeLa cells. © 2019 Elsevier B.V.

Inorganica Chimica Acta

Vitamin B6 cofactor conjugated rhodamine 6G derivative: Fluorescent turn-on sensing of Al(III) and Cr(III) with bioimaging application in live HeLa cells

One-pot approach was adopted for the synthesis of highly luminescent near-infrared (NIR)-emitting gold nanoclusters (AuNCs) using bovine serum albumin (BSA) as a protecting agent. The vitamin B6 cofactor pyridoxal was conjugated with the luminescent BSA-AuNCs through the free amines of BSA and then employed for the nanomolar detection of Hg2+ in aqueous medium via selective fluorescence quenching of AuNCs. This nano-assembly was successfully applied for the real sample analysis of Hg2+ in fish, tap water and river water. The study also presents chemically-modified cellulosic paper strips with the pyridoxal conjugated BSA-AuNCs for detecting Hg2+ ion up to 1 nM. © 2016 Elsevier B.V.

Biosensors and Bioelectronics

Chemically modified cellulose strips with pyridoxal conjugated red fluorescent gold nanoclusters for nanomolar detection of mercuric ions

Two new Schiff base receptors have been synthesized by condensation of pyridoxal-5-phosphate with 2-aminophenol (L1) or aniline (L2). In DMSO, the receptors showed both chromogenic and 'turn-on' fluorescence responses selectively in the presence of AcO- and F-. However, in mixed DMSO-H2O medium, the receptors showed AcO- selective 'turn-on' fluorescence without any interference from other tested anions including F-. The detection limit for AcO- was found to be 7.37 μM and 22.9 μM using the receptors L1 and L2, respectively. © 2015 Elsevier B.V. All rights reserved.

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Acetate selective fluorescent turn-on sensors derived using vitamin B 6 cofactor pyridoxal-5-phosphate

Pyridoxal-thiosemicarbazide: its anion sensing ability and application in living cells imaging

Journal of Photochemistry and Photobiology B: Biology

Bioimaging application of a novel anion selective chemosensor derived from vitamin B6 cofactor

A novel vitamin B6 cofactor derived anion sensor L for the selective colorimetric detection of acetate has been developed by the condensation of pyridoxal and 2-aminothiophenol. The sensor L showed a noteworthy change in the visible region of the spectrum and was detected by the 'naked-eye' for both acetate and fluoride anions in DMSO but selectively for acetate in DMSO/H2O (88:12, v/v). The anion recognition ability of L was investigated by spectroscopic (UV-vis and 1H NMR) and DFT methods. © 2014 Elsevier Ltd. All rights reserved.

Tetrahedron Letters

Vitamin B6 cofactor derived chemosensor for the selective colorimetric detection of acetate anions

Organic & Biomolecular Chemistry

UV-visible and 1H–15N NMR spectroscopic studies of colorimetric thiosemicarbazide anion sensors

Chem. Soc. Rev.

Anion receptor chemistry: highlights from 2011 and 2012

Journal	Data powered by TypesetRSC Advances
Publisher	Data powered by TypesetRoyal Society of Chemistry (RSC)
ISSN	20462069
Open Access	No