This study was carried out to identify the various phytoconstituents present in the seeds of Mucuna pruriens and also to find its acute oral toxicity. Fresh seeds were procured, shade dried and methanol extract was prepared by Soxhlate method. The yield obtained was 8.67%wt/vol. The phytochemical studies were done by standard protocols of pharmacognosy and the acute toxicity effects by OECD guideline 423. 2000mg/kg of methanol extract was administered by oral route in albino mice weighing about 18-25gm. The wellness parameters, biochemical parameters, haematological parameters were assessed and histopathological studies were done to know the toxic effects of the methanol extract of seeds of MP if any. The phytochemical studies confirmed the presence of Carbohydrates, Proteins & amino acids, glycosides, alkaloids, phytosterols, flavonoids, saponins, tannins and phenolic compounds. The toxicity study results showed that all the parameters were normal and there was no associated morbidity or mortality. Thus we conclude that the methanol extract of Mucuna pruriens has a LD50 value above 2000mg/kg and the drug is safe under therapeutic doses. © 2016, Global Research Online. All rights reserved.