A high speed auto catalytic copper plating bath has been developed with Naficillin and Oxacillinantibiotics as accelerators for auto catalytic copper plating process. The acceleration effect of the compounds was determined by weight gain and electrochemical method. Both compounds improved the rate of deposition to considerable extent by adsorbing strongly on the steel surface. The adsorption of the accelerators was found to obey Langmuir adsorption isotherm. The quantum mechanical parameters further justified the impressive performance of accelerators through their effective adsorption on metal surface. © 2015, Sphinx Knowledge House. All Rights Reserved.