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Red light-triggered photoreduction on a nucleic acid template
, J. Rühle, M. Schikora, N. Deussner-Helfmann, M. Heilemann, T. Zatsepin, P. Duchstein, D. Zahn, G. Knör, A. Mokhir
Published in Royal Society of Chemistry
PMID: 32728684
Volume: 56
Issue: 69
Pages: 10026 - 10029
Conjugate Sn(iv)(pyropheophorbide a)dichloride-(peptide nucleic acid) catalyzes reduction of azobenzene derivatives in the presence of complementary nucleic acid (NA) upon irridiation with red light (660 nm). This is the first red light-induced NA-templated photoreduction. It is highly sensitive to single mismatches in the NA-template and can detect down to 5 nM NAs. This journal is © The Royal Society of Chemistry.
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JournalData powered by TypesetChemical Communications
PublisherData powered by TypesetRoyal Society of Chemistry