Image fusion is the process of combining relevant information from two or more images into a single fused image. The resulting image will be more informative than any of the input images. The fusion in medical images is necessary for efficient diseases diagnosis from multimodality, multidimensional and multiparameter type of images. This paper describes a multimodality medical image fusion system using different fusion techniques and the resultant is analysed with quantitative measures. Initially, the registered images from two different modalities such as CT (anatomical information) and MRI - T2, FLAIR (pathological information) are considered as input, since the diagnosis requires anatomical and pathological information. Then the fusion techniques namely Redundancy Discrete Wavelet Transform (RDWT) and Contourlet Transform are applied. Further the fused image is analyzed with five types of quantitative metrics such as Standard Deviation (SD), Entropy (EN), Overall Cross Entropy (OCE), Ratio of Spatial Frequency Error (RSFE), and Power Signal to Noise Ratio (PSNR) for performance evaluation. From the experimental results we observed that RDWT method provides better information (quality) using EN metric and the Contourlet Transform gives the difference in source to the fused image using OCE metric and also the fused image obtained from the proposed fusion techniques has more information than the source images are proved through all metrics. © 2010 IEEE.