Here, we demonstrate the combined influence of Intrapulse Raman Scattering (IRS), Self-Steepening (SS) and negative Third Order Dispersion (n-TOD) on soliton interaction. The peculiar particle nature of soliton results in interaction of in-phase adjacent pulses while helps in deviation of out-of phase pulses. We show how the interaction of the soliton can be avoided due to combined effect of IRS, SS and negative TOD as these effects apart from various nonlinear dynamics results in shifting of pulses. The interaction point of solitons in 160 Gbps system is found to be at 24.22Km for an initial relative spacing of qo=5.28 using Perturbation theory. This in-phase soliton pair tracing inside the fiber in noted using Split-Step Fourier Transform. Further, impact of interaction is realized in 160 Gbps telecommunication model which yielded Q=0 at Ip depicting perfect interaction resulting in bit error without influence while yielded fair Quality facto of 112.375, 124.59, 93.57, 75.12, 63.23 and 46.97 with influence for various TOD values of -0.03, -0.04, -0.05, -0.06, -0.07 and -0.09 ps3/Km and TR=4fs demonstrating no interaction. © 2015 SPIE.