This paper aims to implement the concept of preserving the Confidentiality and Integrity of DICOM Images Using Cryptographic Algorithms. This work uses two types of cryptographic algorithms namely AES (Advanced Encryption Standard) and Blake Hash Function. Using these algorithms, we implement and check the confidentiality and integrity of DICOM images. Our proposed system also ensures that the images are transferred from one hospital database to another in a secure manner and the system will be able to tackle any changes while the image is being transferred. The initial concern of the system lies in providing confidentiality in the communication of the images which can be done using AES algorithm. The integrity can be provided using Blake Hash Function. The comparative analysis of AES with other algorithms such as Triple DES, IDEA, Blowfish and SEED with respect to their execution time is also done. In this work, DICOM files are taken as input and then kept in the encrypted format for storage purpose and also they can be sent over the network in the encrypted format. © 2019 Elsevier Ltd. All rights reserved.