Self-esteem, a feeling of self-worth is an essential quality that promotes the self confidence and helps the individuals to handle stressful situations without anxiety and hassles. As student nurses are the beginners in the nursing profession, the nurse educators should help them face the demands of profession with courage and confidence. Thus the present study was aimed at assessing the self-esteem and anxiety among the student nurses. Quantitative non experimental design was used. The 52 participants were selected by non probability purposive sampling method. Majority 81% had normal self-esteem and 10(19%) had low self-esteem, and 58% were normal without anxiety, 10 (19%) with moderate anxiety, 8(15%) with mild anxiety and only 4(8%) with severe anxiety. There was no significant difference in the self-esteem and anxiety between the groups. There was a negative correlation between self-esteem and anxiety with r = -0.303 and significant at p<0.05. © 2016, Indian Journal of Public Health Research and Development. All rights reserved.