Detection of epileptic area from T2 weighted image of MR Image was performed by calculating the volumes of the brain structures. Atlas based segmentation is used for the segmentation of brain structure. The volume of each part of brain is calculated, and the ratio of right hemisphere of the brain to the left hemisphere of the brain is determined. The ratio of normal brain will be equivalent to 1, but in case of epileptogenic areas the ratio will increase or decrease. The results obtained will be correlated with the original diagnosis result which was already available. The area marked by our method was correlated with the area marked by the original diagnosis. The conclusion was validated by the calculation of true positive, true negative, false positive and false negative point. © Research India Publications.