Silicon is a beneficial element to improve the biological process, growth, development, and crop productivity. The review mainly focuses on the advantage of crops supplemented with silicon, how Si alleviate abiotic stress as well as regulate the genes and proteins involved in metabolic and biological functions in plants. Abiotic stress causes damage to the proteins, nucleic acids, affect transpiration rate, stomatal conductance, alter the nutrient balance, and cell desiccation which could reduce the growth and development of the plants. To overcome from this problem researchers, focus on beneficial element like silicon to protect the plants against various abiotic stresses. The previous review reports are based on the application of silicon on salinity and drought stress, plant defense mechanism, the elevation of plant metabolism, enhancement of the biochemical and physiological properties, regulation of secondary metabolites and plant hormone. Here, we discuss about the silicon uptake and accumulation in plants, and silicon regulates the reactive oxygen species under abiotic stress, further we mainly focus on the genes and proteins which play a vital role in plants with silicon supplementation. The study can help the researchers to focus further on plants to improve the advancement in them under abiotic stress. © 2021 Elsevier B.V.