This research study originates from the recent reports how statistics and modeling plays a significant role that establish the viable scenario in modern microbial technology, Microbes like Actinomycetes and bacteria producing extracellular products known as Keratinases and pectinases are biocatalysts which possesses extraordinary specificity, remarkable catalysis power and having enormous pharmacological benefits. They are tremendous and potential to chemical catalysis due to their environmentally friendly character, as against traditional chemical methods, Microbial metabolic processes generally yield products and reduce the use of polluting chemicals by their exploitation in industry with the advancement of scientific and industrial developments Statistical analysis and mathematical modeling regarding microbial exploitation for the production of these potential enzymes is highly attractive for applications and treatment of Keratin ( hair and poultry) and fruit effluents.