In this paper we discussed the basic statistical analysis of the biological data and associated with the demographic profile and biochemical profile of the samples of arthritis. Arthritis is a multi-factorial disorder consisting of more than 100 types of arthritis9, it is really difficult to say that a particular disease is causing that disorder. For determination of Rheumatoid Arthritis (RA) we have used biochemical tests of the 70 individual affected with rheumatoid arthritis. The peripheral blood serum and plasma has been collected using vacutainers containing EDTA, the samples have gone through 5 tests for the determining the pattern of arthritis. By using this method pre-diagnostic measure for arthritis, results have shown us that most of the patient have correlative increase and decrease in their serum and plasma level when the patient is affected with RA. Various test such as Hb, Uric acid, serum glucose, serum calcium levels are used to determine the presence of arthritic profile. The results have found completely based on correlation of the demographic data with the arthritic marker, diabetic marker, lipid marker, kidney function marker, liver marker. The results have found that maximum correlation is shown among the liver marker as its maximum correlation with all the arthritic markers and demographic data. © 2020, Institute of Medico-Legal Publications. All rights reserved.