Recently, many studies have been oriented towards improving methods and efficiency of recovery from different fruit industry wastes. The investigations carried out were mainly aimed at evaluating Pectin content, Protease activity, Protein Levels, antioxidant potential and melanin composition of air-dried medicinally significant domestic fruit peels (Gooseberry (Phyllanthus emblica), Apple (Malus domestica), Redbanana (Musa Acuminata), Jujube (Ziziphus Zizyphus), Papaya (Carica), Guava (Psidium), Avocado (Persea Americana), Watermelon (Citrullus Lamatus), Muskmelon (Cucumis Melo), Kiwi fruit (Actinidia Delicosia), Orange (Citrus Limetta), Pineapple (Ananas Comosus), Mango (Mangifera), Pomegranate (Punica Granatum), Sapota (Manilkara Zapota) and their extracts. And a brief statistical analysis of the different parameters being estimated was carried out using a software called Statistics Calculator.. In the experiments accomplished, the highest Protease activity was found in peel of Jujube (2.61%) followed by Pineapple and Papaya Peels (1.84% and 1.58% respectively). Highest concentration of protein was also found in Kiw peel (1.79%) where as the highest antioxidant concentration was observed in the peel of Gooseberry (2.39%). Also the maximum levels of melanin formation was noted in the peels of Mango peel (2.19%).Highest Glucosinolate percentage concentration was found in Guava peel (3.87%). Elevated levels of % pectin was also noted in Papaya peel (5.32%). We failed to reject the null hypothesis H0 for the Chi-square test of independence with P value < 0.99 for different estimations made in the fruit peels to learn that the percentage concentration values for Protein, Protease, Antioxidant, Melanin, Glucosinolate and Pectin are strictly independent of each other.