In this research work machinability studies on stainless steel (SS-107.12) implant by wire electrical discharge machining (WEDM) process was studied. The effect of heat affected zone (HAZ), mechanical load experienced and chemical effects after implantation are the significant factors influencing the degradation of machined surface. The metallurgical behaviour of the machined implant is investigated in detail. The experiments are conducted based on design of experiments by considering the input factors like pulse on time, pulse off time and voltage. The influencing responses measured are material removal rate and surface roughness. Further, the machined samples are subjected to metallurgical characterisation, using scanning electron microscope (SEM), spectroscopic (EDS) analysis and atomic force microscope (AFM). From the results it is observed that, increase in voltage has produced better surface finish and reduced the material removal rate (MRR). Copyright © 2020 Inderscience Enterprises Ltd.