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Synthesis and insecticidal activity of acridone derivatives to Aedes aegypti and Culex quinquefasciatus larvae and non-target aquatic species
, Bharathi A, Al-Dhabi N.A, Arasu M.V,
Published in Springer Science and Business Media LLC
PMID: 28059104
Volume: 7
Issue: 1
Pages: 1 - 6
A serious Mosquito borne yellow fever is one of the grave diseases which affect the major population. Since there is no specific treatment for yellow fever, there is a necessity to develop an effective agent. The series of acridinone analogues 3 to 5 were synthesized with help of non-conventional microwave heating and confirmed by respective spectral characterization. 5c and 3b showed highest activity to kill 90% of larvae against A. aegypti and C. quinquefasciatus, respectively. Also the active products were treated to check the mortality of non-target aquatic species. Through the reports of the larvicidal bioassay, compounds 3b against C. quinquefasciatus whereas 5c against A. aegypti were found to be more active. By keeping this as a platform, further extension of the work can be done to find out a valuable drug for controlling disease vectors. © The Author(s) 2017.
About the journal
JournalData powered by TypesetScientific Reports
PublisherData powered by TypesetSpringer Science and Business Media LLC
Open AccessYes