Aliovalent ion substituted fluorapatite of formula Bi0.5Na0.5Ca4(PO4)3F was synthesized by co-precipitation method and characterized by powder X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy and energy dispersive X-ray spectroscopy. The catalytic activity of the synthesized compound was tested on one pot multicomponent reaction (Biginelli reaction) for the synthesis of 3,4-dihydropyrimidin-2(1H)-one and its derivatives. The compounds were confirmed by spectroscopic techniques and melting point. An enhanced yield was observed with this catalyst for the condensation of ethyl acetoacetate, urea and benzaldehyde compared to unsubstituted fluorapatite.

Sumathi S

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Buvaneswari G

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

Reaction Kinetics, Mechanisms and Catalysis

Copper substituted hydroxyapatite (Ca10-xCux(PO4)(6)(OH)(2) (x=0.05-2.0), and fluorapatite Ca10-xCux(PO4)(6)(F)(2) (x=0.05-2.0) were synthesized by co-precipitation method. The synthesized compounds were characterized by powder X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy and thermo gravimetric analysis. The antimicrobial activity of the synthesized compounds were tested against the organisms Escherichia coli (Gram negative bacteria), Staphylococcus aureus (Gram positive bacteria) and Candida albicans (yeast) quantitatively by spread plate method. 100% reduction in the number of colonies were observed with Ca10-xCux(PO4)(6)(F)(2) (x=0.15-0.5) against E. colt. This material can be considered as good antibacterial agent for bone implantation.

Ceramics International

Copper substituted hydroxyapatite and fluorapatite: Synthesis, characterization and antimicrobial properties

Mono, di and trivalent ions containing hydroxyapatite of the formula BiNaCa 3(PO 4) 3OH has been synthesized and the compound's catalytic activity in three component Biginelli condensation was studied. The compound was characterized by powder XRD, FT-IR, SEM and TGA/DTA techniques. The unit cell dimensions of the compound were determined to be a = 9.412(2) , C = 6.92(2) and the unit cell volume is 530.9 3. The substituted hydroxyapatite phase showed enhanced reactivity in the one pot synthesis of 3,4-dihydropyrimidin-2(1H)-one by Biginelli reaction and resulted in an increased yield of the product. © 2012 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

Synthesis of apatite structure based BiNaCa3(PO4)3OH and its application for condensation reaction

Research on Chemical Intermediates

Phthalimide-N-sulfonic acid: a new and efficient organocatalyst for the Biginelli reaction under solvent-free conditions

Catalysis Letters

Synthesis of Dihydropyrimidinones/Thiopyrimidinones: Nafion-Ga, an Efficient “Green” Lewis Acid Catalyst for the Biginelli Reaction

Monatshefte für Chemie - Chemical Monthly

Imidazole functionalized magnetic Fe3O4 nanoparticles as a novel heterogeneous and efficient catalyst for synthesis of dihydropyrimidinones by Biginelli reaction

Synthesis, characterization and catalytic activity of modified fluorapatite towards the multicomponent one-pot Biginelli condensation

Journal	Data powered by TypesetReaction Kinetics, Mechanisms and Catalysis
Publisher	Data powered by TypesetSpringer Science and Business Media LLC
ISSN	1878-5190
Open Access	0