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Tetrabutylammonium Bromide (TBAB) Promoted Metal-Free Synthesis of 2H-Indazolo[1,2-b]Phthalazinetriones and Pyrazolo[1,2-b]Phthalazines from Benzylalcohol through Aerobic Oxidation, Sequential Addition-Cyclization with Phthalhydrazide and β-Diketones
Published in Informa UK Limited
Pages: 1 - 14
A solvent-free synthesis of 2H-indazolo[1,2-b]phthalazinetriones 4 and pyrazolo[1,2-b]phthalazines 6 scaffolds using benzyl alcohol 1 via TEMPO/CAN and TBAB mediated aerobic oxidation, sequential addition-cyclization with phthalhydrazide 2 and β-diketones 3,5 is reported. The experimental strategy offers several advantages, such as simple workup, inexpensive chemicals without any use of solvents, and short reaction time.
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About the journal
| Journal | Polycyclic Aromatic Compounds |
|---|---|
| Publisher | Informa UK Limited |
| Open Access | No |
Authors (1)
Ethiraj K R- A study of antioxidant potential of Perilladehyde
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