With the wide use of smart devices, smart phones, sensors and wireless technology, the Internet of things has changed the perspective of communication and handling of information over the Internet. The devices are used to measure health attributes, to automate the health therapies or to monitor and track real time health attributes. Since all the devices are connected to high speed Internet and smart-phones, people have started to monitor health attributes and medical needs through mobile applications. Such integration of smart devices, Internet and mobile applications results an emerging use of telemedicine and telehealth through Internet of Medical Things (IoMT).Security is concern as IoT application area is evolving vastly long with attacks on devices. Interconnected devices has many application in smart grid, health, military, computing area, daily day-today life like smart vehicle, home, security application etc. Intelligent nodes and platform are working together without human interference in them. Enormous security and privacy threads of IoT applications arise due to ubiquitous and dynamic nature of IoT. Protocols like 6LoWPAN, providing security on communication level that is machine-to-machine communication security through authentication and authorization to void the security attacks on network. To provide the security as communication level, to nullify the security breaches on network, proposed system provides the mutual authentication between M2M devices. Registration, authentication, and key establishment can be done for communication of M2M devices in 6LoWPAN. © 2018 IEEE.