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Water-mediated green synthesis of PbS quantum dot and its glutathione and biotin conjugates for non-invasive live cell imaging
Vijaya Bharathi M, Maiti S, Sarkar B, Ghosh K,
Published in The Royal Society
Volume: 5
Issue: 3
This study addresses the cellular uptake of nanomaterials in the field of bio-applications. In the present study, we have synthesized water-soluble lead sulfide quantum dot (PbS QD) with glutathione and 3-MPA (mercaptopropionic acid) as the stabilizing ligand using a green approach. 3-MPA-capped QDs were further modified with streptavidin and then bound to biotin because of its high conjugation efficiency. Labelling and bio-imaging of cells with these bio-conjugated QDs were evaluated. The bright red fluorescence from these types of QDs in HeLa cells makes these materials suitable for deep tissue imaging.
About the journal
JournalData powered by TypesetRoyal Society Open Science
PublisherData powered by TypesetThe Royal Society
Impact Factor1.531
Open AccessYes
Citation StyleVancouver
Sherpa RoMEO Archiving PolicyGreen