The benzo[h]quinolinyl fused-ring of the title compound, C 14H8ClNO, is planar (r.m.s. deviation = 0.016 Å); the formyl group is slightly bent out of the plane [the C- C- C- O torsion angle is 10.7 (4)°].

Mohana Roopan S

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Nawaz Khan F

Dr.Subashini Rajagopal

VIT Business School

Chennai Campus

Hathwar V.R

Ng S.W.

Fulltext

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2-Chloro­benzo[h]quinoline-3-carbaldehyde

Acta Crystallographica Section E Structure Reports Online

In the title compound, C11H10ClNO2· H2O, the organic molecule is roughly planar (r.m.s. deviation = 0.074 Å). In the crystal structure, molecues are linked by O-H⋯O and O-H⋯N hydrogen bonds and weak C-H⋯π and π-π inter-actions [centroid-centroid distance = 3.578 (3) Å] consolidate the packing. A short Cl⋯O contact [3.147 (3) Å] is also observed.

(2-Chloro-8-methoxyquinolin-3-yl)methanol monohydrate

AbstractFor the first time, synthesis of AB ring core of camptothecin synthons such as (2-chloroquinolin-3-yl)methanols (Va-Vg) using zinc oxide nanoparticles is reported. The desired attractive products were obtained in high yields, short reaction time, using a simple work-up procedure with the purification of products by non-chromatographic methods.

Chemical Papers

ZnO nanoparticles in the synthesis of AB ring core of camptothecin

AbstractAn efficient ligand-free cross-coupling reaction of 2-chloro-3-(chloromethyl)benzo[h]quinoline with N-heterocycles such as piperidin-4-one, 4(3H)-pyrimidone, and ethyl 6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline-3-carboxylate using a catalytic amount of ZnO nanorods as a recyclable catalyst and KOH as the base in DMSO under reflux at 110°C is reported.

ZnO nanorods catalyzed N-alkylation of piperidin-4-one, 4(3H)-pyrimidone, and ethyl 6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline-3-carboxylate

Journal of Applied Crystallography

publCIF: software for editing, validating and formatting crystallographic information files

Journal of Supramolecular Chemistry

X-Seed — A Software Tool for Supramolecular Crystallography

HETEROCYCLES

The Synthesis of Pyridines, Quinolines and Other Related Systems by the Vilsmeier and the Reverse Vismeier Method

2-Chlorobenzo[h]quinoline-3-carbaldehyde

Journal	Acta Crystallographica Section E Structure Reports Online
Publisher	International Union of Crystallography (IUCr)
ISSN	16005368
Open Access	Yes