Past few decades, nanotechnology plays an important role to overcome the usage of traditional materials by improving the multifunctional material complex models. In the last two decades, the researchers have shown a keen interest on developing the complex models on nanofluids by considering the different particles or shapes or sizes with different designs. This review summarizes the theoretical and experimental investigations and developments in nanofluids. © 2016, International Journal of Pharmacy and Technology. All rights reserved.