The present study was aimed to evaluate the antioxidant potential and antibacterial activity of methanol extract of flowers of Couroupita guianensis. Flowers of Couroupita guianensis were collected and identified by a botanist. A Methanol extract of the dry pulverized flowers of Couroupita guianensis was obtained by the Soxhlet cold extraction method. The methanol flower extract was subjected to a preliminary phytochemical screening by standard methods. In vitro antioxidant activity was assessed by 1, 1-diphenyl-2-picryl hydrazyl (DPPH) scavenging assay and measuring hydrogen peroxide radical scavenging activity. Ascorbic acid was used as the standard antioxidant for comparison. The antibacterial activity of flowers was investigated by well diffusion method. Phytochemical analysis of the extract showed the presence of major classes of phytochemicals alkaloids, phenolic compounds such as flavonoids, tannins and saponins. Couroupita guianensis methanolic extract showed the highest reducing capacity. The antibacterial activity of plant extract was found significant. The results of our study suggest that flowers of Couroupita guianensis possess potent antibacterial activity and are a good source of natural antioxidants. Further study is required to identify the chemical compounds responsible for their antibacterial activity.