During surgical operations in the eye, metallic materials may come in contact with tears. These metals/alloys may undergo corrosion when they contact the tears. The corrosion resistance of a Ni –Cr alloy in artificial tears in the presence of excess of glucose and sodium chloride has been evaluated by electrochemical studies such as polarization study and AC impedance spectroscopy. It is observed that when the sodium chloride level or glucose level in tears increases, the corrosion resistance of Ni –Cr alloy in artificial tears is not affected. It is interesting to note that the corrosion resistance of Ni –Cr alloy in artificial tears rather increases. Hence when there is an increase in glucose level of sodium chloride level in tears, the surgical instruments may be of Ni –Cr alloy. © 2019, Russian Association of Corrosion Engineers. All rights reserved.