The purpose of this study is to analyze the influence of wall flexibility and cross diffusion on the peristaltic transport of a MHD dissipative fluid in uniform channel in the presence of Joule heating. Dual solutions are obtained for aligned and transverse magnetic field cases. The exact solution is obtained for stream function and velocity. Further, shooting process is employed to solve the energy and concentration equations. The influence of main parameters on the present flow is explained graphically. The increase in magnetic field decreases the velocity of the fluid. Also Dufour and Soret numbers enhances the temperature while they reduses the concentration field. © 2017 Published under licence by IOP Publishing Ltd.