The present article has been arranged to study the Hall current and Joule heating effects with thermal radiation on peristaltic flow of nanofluid in a channel with flexible walls. Convective conditions for heat transfer in the formulation are adopted. Viscous dissipation in energy expression is taken into account. Resulting differential systems after invoking small Reynolds number and long wavelength considerations are numerically solved. Runge-Kutta scheme of order four is implemented for the results of axial velocity, temperature, and concentration. Outcomes of new parameters like Brownian motion parameter, thermophoresis parameter, thermal radiation parameter, Prandtl number, and Eckert number on the physical quantities of interest are discussed. It is found that the influence of thermal radiation parameter and the Biot number on the temperature is the same fashion. © Springer Nature Switzerland AG 2019.