Cognitive skills are human’s mental skills which help in processing and acquiring knowledge through reasoning, perception and intuition. Cognitive load is associated with an understanding of visualization by enabling us to ingest and interpret. The major influence of the cognitive process is working memory that gets burdened when an individual’s workload increased. Hence, cognitive load can be used as a means to measure the efficacy of visualization. There are numerous physiological signals and imaging modalities available to examine the cognitive workload of an individual. In this study, the various modalities used to examine cognitive performance of the subjects and corresponding classifier model were discussed. The classifier model is intended to link the psychological and physiological data to examine an individual’s cognitive workload conditions. This approach paves a way for the researchers and developers to estimate the cognitive workload in a quantitative platform. © 2019, Research Journal of Pharmacy and Technology. All rights reserved.