The objective of the study is to examine the relationship between critical success factors of total quality management implementation and business performance. A survey method of data collection was adopted to collect primary data from small-scale manufacturing organisations in a regional manufacturing cluster. The two-step structural equation modelling approach is followed to examine the relationship between critical success factors of total quality management implementation and business performance. The study identified seven critical success factors such as top management commitment, customer focus, strategic planning, process management, people management, leadership, and supplier management which play a major role in determining the success of quality management practices. The study also found that there is a strong positive relationship between total quality management practices and business performance, and contributes to the growing body of literature. © 2019 Inderscience Enterprises Ltd.