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Functional Foods
Shihabudeen H.M.S, Priscilla D.H,
Published in Apple Academic Press
Pages: 289 - 314
In individuals with type 2 diabetes, nutrient intake related first-phase insulin response is severely diminished or absent resulting in persistently elevated postprandial glucose (PPG) throughout most of the day [1]. This is due to the delayed peak insulin levels which are insufficient to control PPG excursions adequately [2]. Postprandial hyperglycemia is a major risk factor for micro-and macro vascular complications associated with diabetes [3,4] and so controlling postprandial plasma glucose level is critical in the early treatment of diabetes mellitus and in reducing chronic vascular complications [5]. The acute glucose fluctuations during the postprandial period exhibits a more specific triggering effect on oxidative stress than chronic sustained hyperglycemia which suggests that the therapy in type 2 diabetes should target not only hemoglobin A1c and mean glucose concentrations but also acute glucose swings [6,7]. © 2014 by Apple Academic Press, Inc.
About the journal
JournalFunctional Foods: The Connection Between Nutrition, Health, and Food Science
PublisherApple Academic Press
Open Access0