In this study we have reported the efficacy of the composite biomaterials made of soya protein and sago starch crosslinked with gluteraldehyde (SGSY-G) as temporary wound-dressing materials using the rat as an animal model. Full-thickness excision wounds were made on the back of male rats weighing about 150 -200 g. The dressings were applied on the wounds and changed periodically at an interval of 4 days with the respective material. The wounds treated with SG-SY-G healed completely on 20th day after wound creation, whereas control showed complete healing only on the 25th day. Biochemical studies revealed a significant increase in total collagen, hexosamine and uronic acid contents in the granulation tissues of the treated wounds. The SG-SY-G composite acted an excellent wound dressing material, thereby absorbing excess exudates, and maintained a moist environment at the wound site. The enhanced wound healing in the experimental animals was reflected in the increased rate of wound contraction. The results of the histological and mechanical studies of the experimental groups revealed that reepithelialization and remodeling of the skin have been achieved by providing a moist environment at the wound site by the biomaterials and thereby hastening the migration of keratinocytes.