Manufacturing industries all around the world have embraced the philosophy of lean thinking. The realm of “lean” is no longer limited to shop floor; it has propagated to almost every aspect of business. Thus, lean thinking is now applicable to complete supply chain. This paper investigates the interrelationships between pillars and constructs of a proposed framework of lean supply chain management in Indian manufacturing sector. The results establish a mental model of framework of lean supply chain using interpretive structural modeling and path analysis. © 2016 Chinese Institute of Industrial Engineers.