Detonation gun spray coating method (D-Spray) is an effective method of coating process [1]. The surface property of material will be enhanced by deposition of coating powders such as metal oxides and ceramics like aluminium oxides, tungsten carbide, nickel chromium etc. which improves micro hardness, corrosion and wear resistant resistance property. This coating process is applicable in different engineering sectors such as aviation industry, marine industry, biomedical industry etc., In this Experimental study the Process parameter optimization of D-spray coating process with different coating powder was done by Taguchi design of experiment [2] and interrelationships among multiple response was analyzed with Grey relation Analysis [2] in order to find the optimized processing conditions and to get higher quality of coating. Micro hardness, Wear resistant, Surface roughness are the multiple responses estimated for various combinations of parameters and the optimum process parameters were obtained. © (2014) Trans Tech Publications, Switzerland.