Kalainathan S

Department of Physics

School of Advanced Sciences

Vellore Campus

Bharath D

Anbuselvi D.

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

Journal of Materials Science: Materials in Electronics

A temperature controlled chemo-, regio- and diastereoselective synthesis of enones and Mukaiyama aldol reaction have been developed using sterically hindered CDD with organosilane as a catalyst.

New Journal of Chemistry

Temperature-controlled Mukaiyama aldol reaction of cyclododecanone (CDD) with aromatic aldehydes promoted by TMSCl via the (TMS)3Si intermediate generated in situ

The direct aldol condensation of benzaldehyde to cyclododecanone (CDD), catalyzed by NaOH is expected to yield bis-benzylidene cyclododecanone, but we interestingly ended up with novel β-hydroxy carbonyl compounds and monobenzylidene cyclododecanone derivatives in the cases of 2-halo substituted benzaldehydes. This exceptional behaviour is due to the capability of the CDD ring to exist in the zwitter ionic form. The formation of monobenzylidine derivatives can be due to less stable hydrogen bonds between -OH and -CO groups, electrostatic interaction between aldehyde substituents and metal enolates and the bulkiness of the benzaldehyde ring substituents. We extensively optimized the reaction conditions using different solvents and alkali metal hydroxide catalysts and we are getting high yield, regio-specificity and high diastereoselectivity (anti-aldol) in β-hydroxy carbonyl compounds. The representative crystal structures were examined and they suggest the tendency of anti-aldol compounds to form supramolecular helical motifs. The β-hydroxyl carbonyl derivatives form supramolecular helices via O-H⋯O hydrogen bonds with two anti-aldol units per turn and a pitch of ∼6 Å. The cyclododecanone ring adopts the minimum energy [3333] square conformation. The nucleophile will attack only from the less hindered side of the carbonyl group in the CDD ring. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.

Direct anti and regio-specific aldol reactions of cyclododecanone catalyzed by alkali metal hydroxides: implications for supramolecular helical design

Applied Optics

All-optical switching in Sagnac loop mirror containing an ytterbium-doped fiber and fiber Bragg grating

Optics Express

Robust disparity estimation based on color monogenic curvature phase

Analysis of optical switching in a Yb3+-doped fiber Bragg grating by using self-phase modulation and cross-phase modulation

Studies on thermal nonlinear optical effects on cyclododecanone crystals for IR optical switching application

Journal	Data powered by TypesetJournal of Materials Science: Materials in Electronics
Publisher	Data powered by TypesetSpringer Science and Business Media LLC
ISSN	0957-4522
Open Access	0