Hydroxyapatite doped with disparate ions is synthesized by Sol-gel technique. Hydroxyapatite is a widely bio-ceramic material for orthopedics and dental applications with weak mechanical strength. The hydroxyapatite doped with various ions which is often reported to enhance mechanical strength and to control bacterial infections. The aim of the work concentrates to improve the hardness of the material. Antibacterial activity enhances with the ions which combine with hydroxyapatite. These effects noticeably reveal that the hydroxyapatite can be well utilized with doping ions in order to develop their efficiency against the various bacterial strains. The effect of co-dopants investigated on their phase structure, bond formation, surface and optical properties are studied using X-ray diffraction technique, Fourier Transform Infra-red analysis, Atomic Force Microscopy and Ultraviolet–Visible spectroscopy. The crystalline size of all the synthesized materials varies from 39 to 49 nm. All the composites exhibit hexagonal crystal structure. The functional groups confirm the bonding formation of prepared samples. The surface roughness of hydroxyapatite were successfully analyzed and observed that the dopants increase the roughness. The dielectric property explains the space charge polarization is present at low frequency and negative temperature coefficient of resistance in the prepared samples. The addition of ions improves the mechanical properties of host materials, which well suitable for coating on implantation devices and for various medical applications. © 2019 Elsevier B.V.