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Synthesis and DNA Binding Study of Zinc (II) Co-Ordination Complexes
Inamdar P.R, Hazarika J, ,
Published in Trans Tech Publications, Ltd.
Volume: 584
Pages: 401 - 405
Since the discovery of cisplatin, transitional metal complexes have been proven to be potent DNA intercalating agents. As zinc being an active core of binding site of some metalloenzymes, the synthesis of structurally similar zinc (II) complexes is on the offing. They are found to be potent DNA intercalating and cleaving agents. Thus, the current study is focused on synthesis of zinc (II) complexes using amino acid / schiff bases as ligands. The complexes are characterized by FTIR, UV-Visible and mass spectral studies and assessed for their DNA binding study using λ DNA by Gel electrophoresis.
About the journal
JournalAdvanced Materials Research
PublisherTrans Tech Publications, Ltd.
Open Access0