The interaction of the mixed convective boundary layer nanofluid flow with the thermal dispersion of heat and mass transfers in an isothermal vertical wedge implanted in a porous medium has been investigated. Using nonsimilarity solutions, the energy equation, which includes the thermal dispersion, accelerates fully nonlinear partial differential equations. The governing coupled nonsimilarity equations have been solved numerically. An examination of present outcomes is made with the existing outcomes in the literature, and our outcomes are in great concurrence with the known outcomes. A parametric review demonstrating the impact of various physical parameters is performed. The set of numerical outcomes for the velocity, temperature, and nanoparticle concentration profiles, as well as the local Nusselt number and a nanoparticle Sherwood number, has been displayed graphically to indicate interesting features of the solutions. It is observed that the heat transfer rate increases as an increasing function of the thermal dispersion parameter for increasing the values of . This result may be useful in thermal dispersion flow switches because the flow rate of fluid increases and there is a cooling effect due to the fluid moving past the temperature scale. © 2020 Begell House Inc.. All rights reserved.