The tibia bone or shank bone is the bigger and stronger of the two bones in the leg below the knee in vertebrates, and it associates the knee with the ankle bones. 3D model is proposed to improve the performance of non-linear analysis in tibia deformation from 2D DICOM Computer Tomography image. Materialize Interactive Medical Image Control System (MIMICS) software is used to develop surface mesh 3D model of tibia bone. Material properties, boundaries conditions and self-weight of the body are the elements used in Finite Element Analysis (FEA) to analyze the nodal solution of displacement, stress and strain using ANSYS software. Proposed model is able to estimate and analyze the displacement, von Mises stress and von Mises strain values of tibia bone by applying various static loads conditions. The results are helpful to develop a rapid prototype (RP) Model of mimic natural bone using bioactive synthetic ceramics material. © RJPT All right reserved.