Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

Department of Communication Engineering

School of Electronics Engineering

Vellore Campus

VIT Unitversity

International Journal of Communication Systems

Guided joint spectrum sensing and resource allocation using a novel random walk grey wolf optimization for frequency hopping cognitive radio networks

Utilizing the available spectrum in a more optimized manner and selecting a proper routing technique for transferring the data, without any data collision, from the sensor node to the base station play a major role in any network for increasing their network lifetime. Cognitive radio techniques play a major role to achieve the same, and when combined with wireless sensor networks the above-said requirements can be greatly accomplished. In this article, a novel energy-efficient distance-based clustering and routing algorithm using multi-hop communication approach is proposed. Based on distance, the given heterogeneous cognitive radio–based wireless sensor networks are divided into regions and are allocated with a unique spectrum. Dynamic clustering through distance calculation and routing of data through multi-hop communication is done. The simulation results illustrate that the proposed algorithm has improved energy efficiency and is more stable. The first node death and 80% node death illustrate the improved scalability. Also, the increased throughput aids in maintaining the residual energy of the network, which further solves the problem of load balancing among nodes. All the above results combined with half node death analysis show that the proposed algorithm also has an improved network lifetime. © 2018, © The Author(s) 2018.

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International Journal of Distributed Sensor Networks

Energy proficient clustering technique for lifetime enhancement of cognitive radio–based heterogeneous wireless sensor network

Novel natural compounds endowed with sound bioactivities are currently the utmost need as leads toward drug discovery. For the first time, here, we report the presence of Amentoflavone (biflavonoid) in the leaves of Cassia fistula L. Structural characterization was carried out using ultraviolet–visible spectrophotometer, Fourier transform infrared, nuclear magnetic resonance, and thin-layer chromatography. The isolated compound was further evaluated for its bioactivity. The compound demonstrated moderate cytotoxicity in liver carcinoma (HepG2) cells, and the comparative analysis for the standard and normal compound has also been validated. Antioxidant potential was assessed by DPPH assay. Furthermore, efficacy of the compound in the aforesaid assays asserts its bioactivity and subsequently its importance as a potent therapeutic. Our study strongly suggests that Amentoflavone present in the leaf extracts of C. fistula L. definitely holds promise in the pharmaceutical industry. © 2017, The Author(s).

Department of Biotechnology

School of Bio Sciences and Technology

3 Biotech

Bioactive Amento flavone isolated from Cassia fistula L. leaves exhibits therapeutic efficacy

Advanced Computing and Communication Technologies Advances in Intelligent Systems and Computing

A Hybrid Approach for Simultaneous Compression and Encryption of an Image in Wireless Media Sensor Networks

Objectives: To implement an effective spectrum access technique using cognitive radio technology with distance based clustering and routing algorithm with in wireless sensor networks and test this algorithm with different scenarios by varying position of the base station. Methods: Network region is divided into parts for allocating the spectrum and topology control, by distance based multi hop clustering and routing algorithm which decides cluster forming strategy on the basis of distance from the base station and route the data with less hops. Findings: The simulation shows, the proposed algorithm was able to provide a better Network Life time with the same amount of initial energy. Also, election of cluster heads on the basis of distance has helped in increasing the stability. And, with different efficient distance thresholds deciding single hop and multi hop communication. Application/Improvements: The proposed algorithm increases the scalability of the network, in comparison to the existing algorithms, by an average of 29%, when the base station is kept at the corner and, by 42.5%, when it is kept away from the corner.

Indian Journal of Science and Technology

Energy Resourceful Distance based Clustering and Routing Algorithm with Competent Channel Allocation Scheme for Heterogeneous Wireless Sensor Networks

2015 International Conference on Applied and Theoretical Computing and Communication Technology (iCATccT)

A novel approach for simultaneous compression and encryption of image in wireless media sensor network

Hepatitis B virus (HBV) is a global threat that killed many human lives. HBV DNA polymerase (HDP) is the key target for antiviral drug treatment. The widely used drug against HBV infection is lamivudine which targets the reverse transcriptase activity of HDP and inhibits the replication of HBV. However, available evidence demonstrated that tyrosine (Y)-methionine (M)-aspartic acid (D)-aspartic acid (D) motif mutations significantly affected the efficacy of lamivudine binding. In particular, M204I mutations affect the drug binding mechanism and cause resistance to lamivudine. Therefore, in the present study we made an attempt to understand the mechanism of lamivudine resistance with the aid of molecular docking and molecular dynamics (MD) approach. The molecular docking results suggest that lamivudine adopts the most promising conformations to the native type HDP by identifying M-204 and Y-203 as a prospective partner for making polar contacts as compared to the mutant type HDP. The MD results showed that the average movements of atoms, especially atoms of the native type HDP– lamivudine complex, were small and displayed fast convergence of energy and charges in geometry. This highlights the stable binding of lamivudine with native type HDP as compared to mutant type HDP. The R2 and RMSF analysis certainly indicates conformational changes in the HDP structure due to M204I mutation. Furthermore the hydrogen bond (H-bond) analysis from the MD study showed that there is decreased number of intermolecular H-bonds in mutant HDP – lamivudine complex as compared to that in native type HDP – lamivudine complex. Overall, our study certainly will pave way to develop new drugs against the drug resistant mutations (M204I) of HBV. © 2015, Springer Science+Business Media New York.

Pharmaceutical Chemistry Journal

Molecular Dynamics Simulation Approach to Understand Lamivudine Resistance in Hepatitis B Virus Polymerase

This project proposes S-MAC, a medium-access control (MAC) protocol designed for wireless sensor networks. Wireless sensor networks use battery-operated computing and sensing devices. The sensor networks are expected to be deployed in an ad-hoc fashion, with individual nodes remaining largely inactive for long periods of time, but then becoming suddenly active when something is detected. S-MAC uses three novel techniques to reduce energy consumption and support self configuration. To reduce energy consumption in listening to an idle channel, nodes periodically sleep. Neighboring nodes form virtual clusters to auto-synchronize on sleep schedules. S-MAC also sets the radio to sleep during transmissions of other nodes and uses in-channel signaling. Finally, S-MAC applies message passing to reduce contention latency for sensornetwork applications that require store-and forward processing as data move through the network. The implementation of S-MAC is evaluated over a sample virtual sensor node network created on the ns2 platform. The experiment results show that, on a source node, an 802.11-like MAC consumes 2-3 times more energy than S-MAC for traffic load with messages sent every 150 ms. © 2012 IEEE.

2012 IEEE International Conference on Computational Intelligence and Computing Research

Energy efficient MAC protocol for energy latency tradeoff in wireless sensor network traffic