For the past two decades, research is under progress seeking alternative materials for titanium and titanium alloys that are used as dental metal restorations. Favorable characteristics of zirconia (ZrO2) ceramic replaced metal-free restorations. This paper provides an insight on ZrO2 potential with a novel silane couplant as a material for dental applications, its mechanical properties, biological characteristics and optical properties. Review shows ZrO2’s tooth like color, mechanical properties, biocompatibility, and low plaque affinity makes as it a suitable implant material. It is designed to produce the shape and functions of natural teeth by filling, denture and implant. Hence, ZrO2 replaced the titanium implants as an alternate with integrated CAD/CAM techniques. The research on surface modification of ZrO2 and its capability to chemically activate the surface is critical in achieving adhesive bonding. The chemical inertness shows difficulty in achieving the reliable bonding between the resin composite cements and ZrO2 ceramics. The silanization of zirconia reported promising results confirming the stability of zirconia in the long-term. © 2021, Springer Nature B.V.