In recent era researchers are mainly focused on silver (Ag) and silver doped nanoparticles due to its vast area of applications which are effectively acts against the microbial activity. Silver nanoparticles (AgNP’s) were one of the metal nanoparticles which have high activity against various diseases causing pathogens to safeguard the environment. However, there is increasing concern related to biological impacts by the use of silver doped nanoparticles on a large scale. The synthesized silver nanoparticles were doped with other chemical reagents by using various physio-chemical methods. The stability of silver nanoparticles was governed by morphological features, capping agents and organic molecules. This review article briefs about the synthesis of silver doped nanoparticles using different methods and their antimicrobial activity. © 2014, Springer Science+Business Media New York.