Industrial cleaners play an important role in the collection of fluffs for centralized waste collection system. Therefore, it has become necessary to find out the design verification and experimental analysis of fluffs collection in actual working condition. This paper deals with the design and experimental investigation of fluffs collection in the cleaner in order to optimize the centralized waste collection system. CFD results of the cleaner were validated by the experimental results from both standard and actual working experimental setup. Finally, performance results of analytical and experimental in both standard and actual working results were compared. It was observed that the volume of fluffs collection at each discharge of the cleaner was 9.7g and the power consumption was 1.682 kW. © Totem Publisher, Inc.