The present work focuses on the experimental vibration analysis of hybrid polymer made composite sandwich panels and investigates the mode shape frequency. All the experimental results are compared with the numerical results by using ANSYS software and the error percentage is found out. In the next part of the study, optimization of parameters affecting the natural frequency has been performed. Optimization was carried out using Taguchi method. In addition, the empirical equations of mode shape frequencies were derived using regression analysis. The results from the derived equations are compared with the numerical mode shape frequencies obtained and a good agreement has been found between them. © 2017 Politechnica University of Bucharest. All rights reserved.