In medicine, a nebuliser is an equipment used to achieve medication in the form of spray breathe into lungs. The general methodological principle of nebulisers is to use oxygen or compressed air or ultrasonic powder, as means to breakup medicinal solutions into smaller mister dews, for direct breath from the mouthpiece of the equipment. The utmost normally used nebulisers are jet nebulisers, which is also known as atomisers . Jet nebulisers are associated with compressors that support compressed air to flow at maximum velocity over a liquefied medication to turn into a mister, which is then breathed in by the patient. The objective of this study is to optimise the jet nebuliser in order to deliver medicine in minor sufficient dews to attain a satisfactory effectiveness of medicated aerosol to reach the lungs. This study concentrates on design optimisation of the nozzle by analysis of flow parameters, evaluation of the path of the fluid flow and determination of the nozzle diameter and flow pressure. © 2021 Inderscience Enterprises Ltd.. All rights reserved.