Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

β-Glucan-binding protein (βGBP) is important for the rational expansion of molecular biology. Here, zinc oxide nanoparticle (ZnONP) was synthesized using βGBP from the crab Scylla serrata (Ss-βGBP-ZnONP). Ss-βGBP-ZnONP was observed as a 100 kDa band on sodium dodecyl sulfate polyacrylamide gel and characterized with UV-vis spectroscopy at 350 nm. X-ray diffraction analysis displayed values consistent with those for zincite. Fourier transform infrared spectroscopy revealed the presence of functional groups, including amide, alcohol, alkane, alkyl halide, and alkene groups. The zeta potential (-5.36 mV) of these particles indicated their stability, and transmission electron microscopy revealed the presence of 50 nm nanocones. Ss-βGBP-ZnONPs were tested at 100 μg/mL against the gram-positive Enterococcus faecalis and gram-negative Pseudomanas aeruginosa using confocal laser scanning microscopy and the bacterial viability assay was also performed. The growth of MCF7 breast cancer cells was inhibited following treatment with 75 μg/mL Ss-βGBP-ZnONPs. Thus, Ss-βGBP-ZnONPs have the ability to control the growth of pathogenic bacteria and inhibit the viability of MCF7 breast cancer cell lines.

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Language

School of Social Science and Languages

Chennai Campus

Department of Biotechnology

School of Bio Sciences and Technology

Vellore Campus

Microbial Pathogenesis

Antibiofilm and anticancer potential of β-glucan-binding protein-encrusted zinc oxide nanoparticles

Eleusine coracana (Finger millet) has high nutritional value with numerous health benefits and is of low cost. Isolation of beta-glucan (βG) from E. coracana (Ec-βG) has gained increasing research attention. UV-vis spectroscopy used to measure the surface plasmon resonance at 361 nm to confirm the presence of polysaccharides (glucan molecules) in Ec-βG. X-ray diffraction analysis of Ec-βG displayed a crystalline nature and confirmed the presence of the βG molecule. Further, the bioactive compounds of Ec-βG were screened using gas chromatography-mass spectrometry. The antibacterial activity of Ec-βG against both Gram-positive (Lysinibacillus fusiformis, Enterococcus faecalis) and Gram-negative (Proteus vulgaris, Shigella sonnei) bacteria were assessed through minimum inhibitory concentrations

Isolation of β-glucan from Eleusine coracana and its antibiofilm, antidiabetic, antioxidant, and biocompatible activities

Cleaner production is a simple defensive mechanism to protect the environment from pollution and depletion of resources. It is also envisioned to minimise the waste and capitalise on natural resources with effective utilization. Solar energy is a natural resource which can be converted into electricity using photovoltaic (PV) system. This article sheds insights on the implementation of solar PV system with interdisciplinary views and analyse motives and barriers for PV adoption by different citizen groups in India. A survey was conducted to understand the people's perception on solar PV energy system and to determine the level of acceptability among the citizens. The survey information was synthesised and consolidated from various perspectives and the result consigns the research findings into technical, human and socio-economic components. The findings were synthesised through cross-cultural, comparative and mixed-method research outcomes by means of Structural Equation Modelling (SEM), Dendrogram diagram and biplot interpretation. Statistical tools such as ‘IBM-SPSS Amos’ and ‘R’ language programming were also used to interpret the results. This article concludes by specifying the barriers that limit the retrofitting interventions, suggests possible measures and policies to overcome such barriers and promote solar energy in India. © 2018 Elsevier Ltd

Department of Thermal and Energy Engineering

School of Mechanical Engineering

Electrical

School of Electrical Engineering

Journal of Cleaner Production

A sociocultural study on solar photovoltaic energy system in India: Stratification and policy implication

Prophenoloxidase is a conserved Cu-containing enzyme acting as a major defense molecule in the immune response of crustaceans. In the present research, we purified prophenoloxidase from the haemolymph of Portunus pelagicus (Pp-proPO) by Blue Sepharose CL-6B chromatography. Pp-proPO exhibited only one band with molecular weight of 75 kDa on SDS-PAGE. The purified Pp-proPO was characterized through X-ray diffraction (XRD) and high-performance liquid chromatography (HPLC). Pp-proPO showed phagocytic activity on the yeast Saccharomyces cerevisiae as well as encapsulation on sepharose CL-6B beads associated with CM sepharose and beads of sodium alginate. Pp-proPO also led to strong agglutination on human erythrocytes. Furthermore, Pp-proPO showed magnified PO activity when altered with activated particles acting as pathogen combined molecular patterns (PAMPs), metal ions or other chemicals. Pp-proPO showed relevant antibiofilm activity on Gram negative bacteria Pseudomonas aeruginosa and Escherichia coli. Overall, the above results allowed us to claim that Pp-proPO play a key role in immune defense mechanisms of P. pelagicus crabs, in particular towards microbial pathogens; notably we added basic information to the functional characterization of Pp-proPO, as well as to understand its immunological role in crustaceans defense systems. © 2018 Elsevier B.V.

International Journal of Biological Macromolecules

Identification, characterization and immune response of prophenoloxidase from the blue swimmer crab Portunus pelagicus and its antibiofilm activity

Journal of Photochemistry and Photobiology B: Biology

Green synthesis of gold nanoparticles using a cheap Sphaeranthus indicus extract: Impact on plant cells and the aquatic crustacean Artemia nauplii

Department of Electrical Engineering

2015 IEEE 13th International Conference on Industrial Informatics (INDIN)

Energy management in smart grid

VIT Unitversity

2011 International Conference on Signal Processing, Communication, Computing and Networking Technologies

A VLSI - ASIC implementation of Fast Hartley transform for OFDM receivers

Advances in Computing and Communications Communications in Computer and Information Science

Review on VLSI Architectures for Optical OFDM Receivers